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Research officer cellular immunology & assay development

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Research officer cellular immunology & assay development

COMPANY OVERVIEW

Glenmark Pharmaceuticals is a research-led, global, fully integrated pharmaceutical company. The group is present in more than 40 countries including the USA and Europe and is undergoing a spin-off to form a new innovative biopharmaceutical company head-quartered in the USA.

Swiss operation of the company encompasses two biological R&D Centers and a GMP manufacturing facility and focuses on the discovery and development of novel biological entities and drugs comprising monoclonal antibodies and proprietary bispecific format in the field of immune-oncology and autoimmune diseases.

Overall we currently have five clinical and three preclinical assets in development based on our proprietary technology platform BEAT® (Bispecific Engagement by Antibodies based on the T cell receptor). Three of them are in Phase 2b, and one asset is likely to enter Phase 2b in FY20. Our molecules and drugs under developments target treatment among others of HER2 positive cancers, multiple myeloma and other malignancies of hematopoietic origin, as well as a variety of solid tumors.

We are looking for highly motivated people who thrive on being challenged and working in an agile, collaborative and multicultural environment to join our multidisciplinary discovery team and play a key role in conducting rigorous, cutting-edge science.

To execute and enrich our ambitious pipeline of projects, we are seeking to hire a

 

RESEARCH OFFICER

CELLULAR IMMUNOLOGY & ASSAY DEVELOPMENT

ROLE OVERVIEW:

The Research Officer will be responsible of designing, performing and analyzing experiments to support the validation of novel biologic targets in immuno-oncology and autoimmune diseases. We are looking for an experienced, highly collaborative, independent and flexible team player for our high-paced dynamic environment.

RESPONSIBILITIES:

 

  • Design, optimize and validate functional immuno-oncology assays including but not limited to immunological multi-color cell surface and intracellular flow cytometric profiling, multiplex cytokine profiling, gene expression profiling, binding assays, primary human cell-based assays for the characterization of novel biological candidates.
  • Perform cell culture, including primary human cultures, development and maintenance of cell lines.
  • Write detailed protocols in English.
  • Participate in day-to-day laboratory management.
  • Perform data analysis on a regular basis and clearly communicate results in English.
  • Maintain experimental records in electronic lab notebook format.
  • Collaborate across functions to validate novel targets
  • Assist with general laboratory duties including lab equipment maintenance, ordering and receiving of lab supplies.
  • Comply with all safety guidelines

     

  • Perform other relevant responsibilities as required.

REQUIREMENTS:

 

  • Minimum of technical degree or equivalent in immunology, cellular biology or related life sciences
  • 3+ years of laboratory experience (industry experience preferred)
  • Solid and demonstrable bench level experience in the development, validation and implementation of immunological assays
  • Hands-on expertise in methodologies, reagents and instruments used for primary cell cultures, flow cytometry (mandatory), ELISA and cytokine analyses
  • Experience with handling primary cells in BSL-2 level facilities, isolation of immune cells from human biological samples (PBMC) is mandatory
  • Practical knowledge in data analysis using standard software (e.g. Excel, GraphPad, JMP, Flow cytometry dedicated software)
  • Experience in antibody discovery and pharmaceutical industry is a plus
  • Fluent English both written and verbal; proficiency in French is a plus
  • Strong organizational skills with the capacity to handle multiple tasks simultaneously
  • Ability to work independently as well as part of a cross-functional team
  • Strong interpersonal communication skills

You will strive with us, a vibrant biotech community at the Biopôle (https://www.biopole.ch/ ) overlooking the beautiful shores of Geneva lake in Lausanne, Switzerland.

Now it is a rare opportunity to join our growing scientific team at the very start of something special. You become a part of the foundation of a new company making yourself an imprint

Address

Route de la Corniche 5 1066 Epalinges

Website http://www.glenmarkpharma.com

2300 La Chaux-de-Fonds / La Chaux-de-Fonds / Epalinges / Neuchâtel

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