Process Development Scientist (Peptide Chemistry) 2 Years Fixed Term position
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We have an exciting opportunity for an experienced Process Development Scientist to join our Synthetic Molecules Technical Development team (PTDC) based in Basel. This is a 2 year fixed term position.
The Synthetic Molecules Technical Development (PTDC) team is in charge of developing the technical aspects of synthetic pipeline molecules and producing the Drug Substance and Drug Product for clinical trials. They have extensive expertise in Drug Substance, Drug Product, and analytical sciences. PTDC works closely with partners in Research and Early Development (pRED / gRED) and the synthetic molecules commercial manufacturing network.
THE OPPORTUNITY
As Process Development Scientist for Peptides, you are responsible for the following:
Process development of peptide manufacturing processes focusing on synthesis. Expertise in chromatography and membrane filtration is an advantage.
Development of cost efficient and robust processes and delivering thorough process understanding by using state of the art science and methodologies to enable lean manufacturing.
Leading a team of associates in a matrix organization to design and develop manufacturing processes.
Working in an interdisciplinary matrix team with scientists from analytics, and manufacturing, process engineering, and microbiology. Coordination of drug substance related activities and representation of DS team in project team
Evaluation of data using state of the art statistical tools and/or applying advanced process modeling.Authoring of scientific reports, patent applications, and regulatory documents.
Scaling up and transfer of processes to manufacturing (inhouse or to CDMOs)
WHO YOU ARE
Ph.D. in Chemistry (PostDoc is a plus) with a minimum of two years of working experience in an industrial setting.
Experience with process development for peptides with focus on synthesis. Experience with enzyme catalyzed synthesis of peptides is a plus.
Experience with downstream process development (chromatography, UF/DF, nanofiltration, TFE) is a plus.
Working style driven by initiative, team focus, responsibility and flexibility. Experience working in a dynamic environment on complex projects with internal and external stakeholders
Excellent organizational skills, self-driven, efficient and reliable attitude.
Our mission is to reliably deliver the pipeline and supply quality products to patients. If you share our values of patient centricity and innovation, we would love to hear from you.
At Roche, more than 100,000 people across 100 countries are pushing back the frontiers of healthcare. Working together, we’ve become one of the world’s leading research-focused healthcare groups. Our success is built on innovation, curiosity and diversity.
Basel is the headquarters of the Roche Group and one of its most important centres of pharmaceutical research. Over 10,700 employees from over 100 countries come together at our Basel/Kaiseraugst site, which is one of Roche`s largest sites. Read more.
Besides extensive development and training opportunities, we offer flexible working options, 18 weeks of maternity leave and 10 weeks of gender independent partnership leave. Our employees also benefit from multiple services on site such as child-care facilities, medical services, restaurants and cafeterias, as well as various employee events.
We believe in the power of diversity and inclusion, and strive to identify and create opportunities that enable all people to bring their unique selves to Roche.
Roche is an Equal Opportunity Employer.
