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Systems Biology Scientist


We believe it’s urgent to deliver medical solutions right now – even as we develop innovations for the future. We are passionate about transforming patients’ lives. We are courageous in both decision and action. And we believe that good business means a better world.

That is why we come to work each day. We commit ourselves to scientific rigour, unassailable ethics, and access to medical innovations for all. We do this today to build a better tomorrow.

We are proud of who we are, what we do, and how we do it. We are many, working as one across functions, across companies, and across the world.

We are Roche.

Systems Biology Scientist

We are seeking a Systems Biologist within the Neuroscience and Rare Disease (NRD) Discovery and Translation Area (DTA) at Roche where we are developing medicines for a range of serious neurological diseases, including multiple sclerosis, Alzheimer’s disease, autism, spinal muscular atrophy, Huntington’s disease, and Parkinson’s disease.

Our lab pursues discovery research and development in neurological, neuropsychiatric and neurodevelopmental disorders using state of the art human genetics, single cell genomics and functional genomics technologies. We work in close collaboration with leading academic groups in USA and Europe, and with experimental research groups in the NRD DTA.

Your responsibilities

  • You will develop new algorithms and apply state of the art methods for to the analyses of single-cell RNAseq and ATAC seq data, and integrative analyses of multi-omics data sets
  • You will implement and optimize successful analyses algorithms, both for the internal pipeline and for use by the broader Roche community
  • You will lead and contribute to the successful progression of both internal and external collaborative projects.
  • You will create user-friendly applications (eg R Shiny apps) for understanding of high dimensional genomics data sets for non-computational experimental researchers in NRD DTA.


  • A PhD or equivalent experience in computational biology, physics, mathematics or a PhD in molecular biology supplemented with extensive formal training in statistics and multivariate data analysis
  • Good programming skills (knowledge of algorithms, data structures, data storage and access technologies)
  • Hands-on experience with the analysis and interpretation of several types of large scale genomics data, such as RNA-seq, ChIP-seq, ATAC-seq, Bis-seq or HiC-seq
  • Familiarity with publicly available genomics datasets and the respective literature
  • Excellent oral and written English communication skills
  • Are you ready to apply? We are looking a person who thinks beyond the job offered - someone who knows that this position can be a rare springboard to many other opportunities at Roche.

Roche embraces diversity and equal opportunity in a serious way. We are committed to building teams that represents a range of backgrounds, perspectives, and skills. The more inclusive we are, the better our work will be.

If you still have questions then please check our FAQs and videos on careers.roche.ch/faq.

Roche is an equal opportunity employer.

Kaiseraugst / Basel

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