Analytical Expert (m/w/d) with Focus on Mass Spectrometry (100%, temporary for 2 years)
Global Technical Development (PTD) is an organization of over two thousand people globally that are integral for the mission of Roche to develop meaningful medicines for patients. Therefore, PTD actively collaborates and develops creative technical solutions to bridge early-stage, late-stage and commercial product needs. The mandate of the group is to reliably deliver the pipeline and supply quality products to patients. The group excels in its work through innovation, teamwork, dedication, and mutual respect and contributes every single day, continuously improving what it does.
The Analytical Research & Development department (PTDC-A) is part of Global Technical Development (PTD) and responsible for analyzing drug substances and dosage forms of synthetic molecule development products. The ultimate goal of our work is a robust control strategy to release pharmaceutical products for clinical trials, and finally for commercial supply.
The “Hyphenated & Special Technologies (HST)” section provides key scientific customer support with Mass Spectrometry (MS), separation sciences and innovative special technologies. More than 20 mass spectrometry experts in HST verify the safety and quality of our drug substances and drug products by identity testing, characterization and quantification of any type of impurities including genotoxic impurities, N-nitrosamines and extractables & leachables.
As an analytical expert in HST you are mainly responsible for the following tasks:
Qualitative and quantitative analytics of organic, ionic and elemental impurities in drug substances, drug products and/or production materials according to the required quality standards (non-GMP or GMP) mainly by GC-MS, Headspace-GC-MS, LC-MS (low and high resolution), ICP-MS and ion chromatography (IC).
You are working approx. 75% of your time hands-on with the different analytical systems and softwares
Development & validation of analytical methods.
Oversight and coordination of analytical requests within a project incl. direct communication to stakeholders and customers.
You will support cross-functional teams (incl. e.g. process development, manufacturing, regulatory affairs) as subject matter expert for identification and quantification of impurities (e.g. in the fields of extractables & leachables, genotoxic and elemental impurities).
Continuous improvement of work processes through the use of digital tools.
As a suitable candidate you bring an apprenticeship as laboratory technician (or other degree such as DUT) with significant work experience in trace analytics or higher education (e.g. Bachelor or Master in natural science - chemistry, pharmacy, food chemistry, environmental chemistry, polymer chemistry or equivalent). Work experience in GC-MS, LC-MS, ICP-MS and IC analytics (e.g. in the fields of research, development, environmental analysis, food and consumer goods analysis and/or polymer analysis) is an advantage. Further qualifications are:
You enjoy the quantification and structure elucidation of impurities on a ppb to ppm level with hands-on experience in the development and optimization of chromatographic methods.
You are interested in data & digital topics and keen on using IT applications to simplify data evaluation and reporting.
You feel comfortable processing different analytical requests in parallel in a pragmatic, proactive and solution-oriented way..
You are an excellent team player with good communication skills, open and curious and you are comfortable working with colleagues from various hierarchical levels.
Very good knowledge of spoken and written English; basics of German are of advantage.
Your complete application includes a current CV and a Motivation Letter.
At Roche, more than 100,000 people across 100 countries are pushing back the frontiers of healthcare. Working together, we’ve become one of the world’s leading research-focused healthcare groups. Our success is built on innovation, curiosity and diversity.
Basel is the headquarters of the Roche Group and one of its most important centres of pharmaceutical research. Over 10,700 employees from over 100 countries come together at our Basel/Kaiseraugst site, which is one of Roche`s largest sites. Read more.
Besides extensive development and training opportunities, we offer flexible working options, 18 weeks of maternity leave and 10 weeks of gender independent partnership leave. Our employees also benefit from multiple services on site such as child-care facilities, medical services, restaurants and cafeterias, as well as various employee events.
We believe in the power of diversity and inclusion, and strive to identify and create opportunities that enable all people to bring their unique selves to Roche.
Roche is an Equal Opportunity Employer.
