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Purification Development Research Technician in Bioprocess R&D

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Acquired by Sobi from Novimmune, EmaCo is Sobi’s platform for research, development and commercialization of immunology therapies. EmaCo SA is part of the Sobi Group. The core asset, Gamifant®  (emapalumab-lzsg), is an interferon gamma (IFN?)-blocking antibody, the first and only FDA-approved treatment indicated for the treatment of adult and pediatric (newborn and older) patients with primary hemophagocytic lymphohistiocytosis (HLH) with refractory, recurrent, or progressive disease or intolerance with conventional HLH therapy.

 

EmaCo is currently seeking a Purification Development Research Technician in the Biopharmaceutical Development and Supply Department. The selected candidate will work within the Purification and Drug Product Development Team, working on lab scale purification process development and characterisation, and will interact closely with other members of Biopharmaceutical Process Development. This is primarily a laboratory-based position.

Purification Development Research Technician in Bioprocess R&D

Acquired by Sobi from Novimmune, EmaCo is Sobi’s platform for research, development and commercialization of immunology therapies. EmaCo SA is part of the Sobi Group. The core asset, Gamifant®  (emapalumab-lzsg), is an interferon gamma (IFN?)-blocking antibody, the first and only FDA-approved treatment indicated for the treatment of adult and pediatric (newborn and older) patients with primary hemophagocytic lymphohistiocytosis (HLH) with refractory, recurrent, or progressive disease or intolerance with conventional HLH therapy.

 

EmaCo is currently seeking a Purification Development Research Technician in the Biopharmaceutical Development and Supply Department. The selected candidate will work within the Purification and Drug Product Development Team, working on lab scale purification process development and characterisation, and will interact closely with other members of Biopharmaceutical Process Development. This is primarily a laboratory-based position.


Key responsabilities

  • Execute antibody purifications at lab scale

  • Perform scale down model and process characterization studies

  • Participate in the development of new purification processes and evaluation of new technologies

  • Perform process analytics such as UV280nm, HPLC (SEC, HIC)

  • Prepare buffers according to internal procedures

  • Record data in a timely manner according to internal requirements

  • Report results on a daily/weekly basis

  • Contribute to writing and reviewing of documents (study protocol and report, QA documents, macro, operating methods, procedures, records)

  • Ensure equipment are properly maintained  and laboratories are properly organized

Minimum requirements

  • Technical degree / Bachelor of Science degree in Biotechnology, Biology or Biochemistry  

  • Experience of purification processes for antibodies (e.g., column packing, chromatography and tangential flow filtration)

  • Experience in use of ÄKTA systems (Avant, Purifier) and Unicorn Software (or equivalent systems)

  • At least 1 year professional experience in purification process development in the biopharmaceutical industry

     

Additional Skills/Competencies

  • Knowledge of analytical methods for mAb characterization (e.g. SDS-PAGE, HPLC)

  • Ability to follow written procedures, to identify and report technical issues and to work within project timelines

  • Attention to detail, thorough and accurate when accomplishing a task

  • Proficient use of Microsoft Office software including Excel, Word and PowerPoint is required

  • Good communication and organizational skills, proactive, conscientious and rigorous

  • Fluency in French and a good level in spoken and written English are required

  • Ability to learn and adapt quickly in a fast moving environment

  • Able to work independently and as part of a team to plan and complete different studies in parallel

           

If your profile matches the above description, please send us your CV and motivation letter in English under the reference DSP-Tech-2019 to the following email address:

hr-recruitment@novimmune.com

 

Adresse

Chemin des Aulx 14 1228 Plan-les-Ouates

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