Toxicology Manager

Job ID:  92540 Country:  Switzerland City:  Geneva Professional area:  Scientific Regulatory Affairs Contract type:  Permanent Professional level:  Experienced Location: 

Geneva, CH, 1202

We are JTI, Japan Tobacco International, and we are present in 130 countries. We have spent years innovating, creating new and better products for the consumers to choose from. This is our business. But not only. Our business is our people. Their talent. Their potential. We believe that when they are free to be themselves, and they are given the opportunity to grow, travel and develop, amazing things can happen.

That’s why our employees, from around the world, choose to be a part of JTI. It is why 83% of employees feel happy working at JTI. And why we’ve been awarded Global Top Employer status, nine years running. 

So when you’re ready to choose a career you’ll love, in a company you’ll love, feel free to #JoinTheIdea. 

Learn more: jti.com

Toxicology Manager

Position purpose:

The Toxicology Manager performs toxicological risk assessments of flavor substances, tobacco ingredients, NTM ingredients and other substances used in the manufacture of conventional tobacco (CP) and reduced risk products (RRP). The incumbent will ensure the scientific integrity of JTI products worldwide and commission product testing to support product stewardship of ingredients, materials and technologies.  The incumbent prepares toxicological profile documentation for submission to worldwide regulatory agencies to ensure compliance of JTI products with current and future legislation.

What will you do – responsibilities:

• Perform toxicological risk assessments of flavor substances, tobacco ingredients, NTM ingredients, packaging ingredients and other substances used in the manufacture of JTI products or third parties, to ensure the scientific integrity of JTI products worldwide.  Harmonize and standardize toxicological evaluation processes within JTI SRA function, to increase the efficiency of the toxicological review processes within the product stewardship program
• Support and preparation of toxicological profile documentation for submission to worldwide regulatory agencies to ensure compliance of JTI products with current and future legislation
• Ensure that JTI risk assessment procedures used for the assessment of various Conventional and Reduced Risk Products are in line with current practices accepted by the scientific community and take into account tobacco industry standards as well as practices used in other consumer product industries
• Provide scientific support to SRA management in the case of specific outside challenges or quality related issues concerning JTI products
• Assess JTI's ingredient and product portfolio with regards to chemical regulations, such as REACH.
• Obtain full chemical, toxicological and environmental data from studies in the public literature and, under guidance of appropiate Director, commission and manage toxicological studies to support the use of chemical substances in JTI's portfolio
• Commission the different tests required under the JTI toxicology program including liaison with contract research laboratories. Support the design and management of any JTI toxicological study
• Represent JTI at external meetings with the tobacco industry and external scientific meetings/organizations (e.g. TMA, CORESTA, scientific conferences, Closely monitor competitor activities and support the development of company positions

Who are we looking for – requirements:

• Degree or PhD in toxicology or other appropriate life science with a minimum of three years risk assessment experience. ERT (European Registered Toxicologist) or DABT (Diplomate of the American Board of Toxicology) certification is a plus
• Experience working within scientific and regulatory affairs for regulated products, experience within the tobacco industry or reduced risk products would be a plus.                                                                                                                         
• Proven knowledge or experience with toxicological risk assessment procedures, toxicological test strategies and statistical analysis
• Knowledge or experience with emerging toxicological and risk assessment technologies such as high throughput in vitro testing, systems and computational toxicology, exposure modeling, alternative exposure systems such as air-liquid interface, etc. are a plus
• Experience with predictive QSAR models for physical/chemical properties and human health toxicological endpoints, such as EPI Suite or the OECD QSAR Toolbox is desirable
• Excellent English communication skills (both written and oral), further language skills would be an additional asset
• Business focused toxicologist with experience of working in complex regulatory environments. Strong team player with excellent communication skills, oral and written. Accompanied with the ability to understand and explain complex scientific and regulatory matters to non-scientists

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