Postdoctoral Fellow or Ph.D. Student Position in the Functional Cancer Genomics Group

Postdoctoral Fellow or Ph.D. Student Position
in the Functional Cancer Genomics Group
Directed by Prof. Jean-Philippe Theurillat
Institute of Oncology Research (IOR)
Bellinzona, Switzerland
www.ior.usi.ch

We are looking for a talented and highly motivated

Postdoctoral Fellow or Ph.D. Student

interested in working on competitive projects in Prostate Cancer Progression.

Publications of the laboratory
https://pubmed.ncbi.nlm.nih.gov

Role Mission
The successful candidate will work as part of a team that is dedicated to
understanding how molecular alterations promote tumorigenesis, and how gathered
insights can be exploited to develop better therapies. The position offers excellent
scientific opportunities in a highly stimulating, interdisciplinary environment involving
close interactions between medical and basic scientists.

More specifically, the candidate will have the opportunity to functionally investigate
and exploit recent discoveries emerging from a prostate cancer transcriptome
atlas (www.prostatecanceratlas.org) using state-of-the-art technologies in ex vivo
organoid cultures, patient-derived xenograft models in vivo, and clinical tissue
samples (e.g., PMID: 34857732). Projects include the follow-up of a thus far
unrecognized protein isoform of an established tumor suppressor protein
implicated in mitochondrial biology as well as putative drug targets aimed at
preventing disease progression.

Your profile
Essentials:

• Strong interest/background in cancer biology metabolism, and mitochondria
• At least one first-author publication for postdocs and a co-authorship for Ph.D.
  student applicants
• Ph.D. or M.D./Ph.D. already obtained or soon-to-be for postdoc applicants
• Strategic thinking, self-initiative, and a strong sense of accountability with an
  ability and willingness to challenge, to be challenged, and to learn.

Desirable:

• Interest/background in biochemistry and related assays (e.g., proximity
  assays, BioID, metabolomic profiling) and confocal microscopy.

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Our commitment
The position is located at the Institute of Oncology Research (IOR) in Southern
Switzerland. The initial appointment with competitive salaries is for at least 1 year -
100%. A longer-term commitment over 4 years and more can be expected.
The IOR is a rapidly evolving, leading center for basic and translational cancer
research located in a brand-new research building with state-of-the-art facilities. It
hosts together with the Institute for Research in Biomedicine (IRB) about 20
complementary research groups and offers daily occasions of interaction with leaders
in the fields of cancer, basic immunology, and cancer immunology.
The IOR and IRB are affiliated with the local University in Lugano (Università della
Svizzera italiana, USI) and run a competitive Ph.D. program with the biomedical
faculty at USI which includes an International Ph.D. Lecture Series with worldwide
recognized opinion leaders and a wide range of training opportunities and courses.

Application
We are looking forward to receiving your comprehensive digital application in English
in a single PDF-File .The application will include a curriculum vitae (with training,
working experience, and publications), two reference letters, and a statement of
research interest (maximum one page).
Please submit your application to: humanresources@ior.usi.ch
Reference in the email object:
yoursurname_JPT_PostDoc or
yoursurname_JPT_PhDStud
Applications sent to different contacts, in other formats, or after the deadline will not
be considered.
More information about the Institute and Prof. Jean-Philippe Theurillat is available at
the following link: www.ior.usi.ch. For inquiry regarding this job please contact: jean-
philippe.theurillat@ior.usi.ch

Deadline
30.06.2024
Starting date summer or fall 2024